This chunky lizard with pink or orange spots is one of the few venomous lizards in the world and the largest lizard native to the United States. Though it is sluggish, the Gila monster is capable of delivering a painful* dose of venom when provoked or stepped on. The venom comes from glands in the lizard's lower jaw, reports the San Diego Zoo. The Gila monster has a strong bite and will often not loosen its grip for several seconds, even chewing to help spread the venom deeper into its victim. (*The gila monster's bite may not be fun, but it's rarely fatal. We've updated this slide to reflect that information.)
If you are bitten by Gila monster, the University of Adelaide Clinical Toxinology Resources group suggests you submerge the lizard in water to break free from its strong jaws.