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    What's this?
Scientist creates lifelike cells out of metal
Researcher says he has created living cells made of metal instead of carbon — and they may be evolving.

By

Bryan Nelson
Fri, Sep 16 2011 at 1:38 AM
 274

Related Topics:

Biotechnology, Research & Innovation, Technology, Science, Science
Droplets of mercury

Photo: p.Gordon/Flickr

Scientists trying to create artificial life generally work under the assumption that life must be carbon-based, but what if a living thing could be made from another element?
 
One British researcher may have proven that theory, potentially rewriting the book of life. Lee Cronin of the University of Glasgow has created lifelike cells from metal — a feat few believed feasible. The discovery opens the door to the possibility that there may be life forms in the universe not based on carbon, reports New Scientist. 
 
Even more remarkable, Cronin has hinted that the metal-based cells may be replicating themselves and evolving.
 
"I am 100 percent positive that we can get evolution to work outside organic biology," he said.
 
The high-functioning "cells" that Cronin has built are constructed from large polyoxometalates derived from a range of metal atoms, like tungsten. He gets them to assemble in bubbly spheres by mixing them in a specialized saline solution, and calls the resultant cell-like structures "inorganic chemical cells," or iCHELLs.
 
The metallic bubbles are certainly cell-like, but are they actually alive? Cronin has made a compelling case for the comparison by constructing the iCHELLS with a number of features that make them function much as real cells do. For instance, by modifying the outer oxide structure of the bubbles so that they are porous, he has essentially built iCHELLs with membranes capable of selectively allowing chemicals in and out according to size, much as what happens with the walls of real cells.
 
Cronin's team has also created bubbles inside of bubbles, which opens the door to the possibility of developing specialized "organelles." Even more compelling, some of the iCHELLs are being equipped with the ability to photosynthesize. The process is still rudimentary, but by linking some oxide molecules to light sensitive dyes, the team has constructed a membrane that splits water into hydrogen ions, electrons and oxygen when illuminated — which is how photosynthesis begins in real cells.
 
Of course, the most compelling lifelike quality of the iCHELLs so far is their ability to evolve. Although they aren't equipped with anything remotely resembling DNA, and therefore can't replicate themselves in the same way that real cells do, Cronin has nevertheless managed to create some polyoxometalates that can use each other as templates to self-replicate. Furthermore, he is currently embarked on a seven-month experiment to see if iCHELLs placed in different environments will evolve.
 
The early results have been encouraging. "I think we have just shown the first droplets that can evolve," Cronin hinted.
 
Though the idea of a strange new metal-based form of life rapidly evolving in a lab somewhere on Earth may sound ominous, the finding could forever change how life is defined. It also greatly improves the odds of life existing elsewhere in the universe, since life forms could potentially be built from any number of different elements.
 
The possibilities are exciting to imagine, even if Cronin's iCHELLs eventually fall short of full-blown living cells. His research may have already blown the door off previous paradigms about the conditions necessary for life to form.

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anonymous
Gee-Gee Jan 25 2012 at 9:50 PM

A step closer to creating a race of bio-mechanoids.

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anonymous
Wowed Jan 21 2012 at 4:08 AM

Just as long as this doesn't lead to a "Battlefield Earth" Sequel, then he would be a mad man!

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anonymous
Just as a curio... Jan 20 2012 at 10:06 PM

Could this, if further developed, become the infamous Grey Goo?

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anonymous
ed mo Jan 19 2012 at 1:27 AM

This is not surprising at all. To think we humans are the only living things is this vast universe. Is ridiculous. WE think we are intelligent and superior today. However thousands of years ago our ancestors created things we have a hard time duplicating today. Why? Everything and anything is possible.

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anonymous
Anonynon Jan 15 2012 at 2:06 PM

And this is how the Stardroid known as Mercury came into being.

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anonymous
Alex Jan 14 2012 at 6:25 PM

Only one question: What is life? Nobody answered it yet in from scientific community.

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anonymous
Guest Jan 25 2012 at 11:18 AM

what doth LLLIFE-IFE-IFE-ife

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anonymous
Intercostaldrama Jan 20 2012 at 8:14 PM

Life is a cycle that presupposes death. A BEL curve distribution from birth to a peak of functional value followed by a gradual decay. The concept of "life-after-death" is a negative value intended to brings some sort of reality to that which is pure fantasy.

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anonymous
Guest Jan 24 2012 at 11:59 PM

Wouldn't that mean my toy robot is alive? Maybe the only fantasy is thinking these scientists are creating life when all they're doing is making a complex gooey robot?

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anonymous
Guest Feb 17 2012 at 5:00 PM
No. This has all the same potential as a cell. It has the selectively permeable needed for homeostatic regulation. Normally this would be osmotic regulation but in the case of non-carbon cells the water fluctuation would probs be different. It can still regulate it's nutrients though, whatever they may be. The "mini-bubbles" it talks about correspond to the Eukaryotic micro-organelles that we all know and love. Perhaps the most exciting part is the self replication. It can make copies of itself
.... More
that I would say means that it can pass down it's genes but obviously no carbon means nothing to make traditional base pairs with so there technically are no genes. A robot could be programmed to make copies of itself but this is a whole different level. It it goes through its environment to find the parts needed to replicate and and does so. It also makes it's own energy from hydrolysis. Like a robot, these can "die", but if they do they will quickly break down and it would be very difficult to find a way to get all the complex chemical reactions going again. They would probably die in the biological sense. PS Has anyone found a good article on iCHELLs that hasn't been dumbed down?
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anonymous
Breck Jan 20 2012 at 4:56 PM

That question has been answered a long time ago. In the simplest of terms, life is cellular in nature and carries out complex chemical reactions. I recommend looking at any basic biology textbook.

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anonymous
Guest Jan 16 2012 at 12:28 AM

you want a scientific description of life? or a philosophical therory? clear that up, then ask agein

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anonymous
T-1000 Jan 11 2012 at 3:29 PM

BUM- BUM- BUM- BUH- BUM

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anonymous
jhs Jan 10 2012 at 4:24 PM

What part of "non-organic" is the saline solution you work with in these so-called live cells? What part of non-organic are the rest of the additives you use to stimulate the processes that are occurring?

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anonymous
Guest Jan 19 2012 at 10:31 PM

In organic chemistry and chemistry in general, something being 'organic' is based on a carbon or hydrocarbon structure.

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anonymous
Greg Jan 10 2012 at 10:16 AM

T-1000

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anonymous
Chuck@hoadskjf.com Jan 10 2012 at 12:04 AM

Eeek, I fear the grey goo, man.

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anonymous
:KJ Jan 08 2012 at 5:42 PM

MMmmmm... lets send these to mars or another hospitable planet, and see if they will evolve into something bigger, better, and stronger. Also SkyNet

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anonymous
BuG Jan 08 2012 at 2:17 PM

I can see my dream! Before I organically die, I want my consciousness transferred.

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anonymous
Guest Jan 30 2012 at 9:33 PM

consciousness doesnt die

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anonymous
Fox Feb 11 2012 at 12:59 AM

It may not die in the sense that your cells do but it does turn off permanently.

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anonymous
johnny t Jan 07 2012 at 8:07 AM

HES going to make a real transformer!! feed it gas!!!! feed it gas!! and oil/ fossil fuels. try that. or he's trying to make the matrix or terminator movie happen.
maybe with a mix of starwars lol.

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sabra's picture
sabra Jan 06 2012 at 1:50 AM

This is a bit scary to say the least...

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anonymous
Aaron Jan 09 2012 at 2:08 PM

Not really, it sounds like they really can't do much, and that the scientists have to give them everything to even function. mostly its just cool, and if it works, a big step fOR humanity.

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anonymous
Guest Feb 11 2012 at 11:35 PM

like a lil baby

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