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    What's this?
Scientist creates lifelike cells out of metal
Researcher says he has created living cells made of metal instead of carbon — and they may be evolving.

By

Bryan Nelson
Fri, Sep 16 2011 at 1:38 AM
 273

Related Topics:

Biotechnology, Research & Innovation, Technology, Science, Science
Droplets of mercury

Photo: p.Gordon/Flickr

Scientists trying to create artificial life generally work under the assumption that life must be carbon-based, but what if a living thing could be made from another element?
 
One British researcher may have proven that theory, potentially rewriting the book of life. Lee Cronin of the University of Glasgow has created lifelike cells from metal — a feat few believed feasible. The discovery opens the door to the possibility that there may be life forms in the universe not based on carbon, reports New Scientist. 
 
Even more remarkable, Cronin has hinted that the metal-based cells may be replicating themselves and evolving.
 
"I am 100 percent positive that we can get evolution to work outside organic biology," he said.
 
The high-functioning "cells" that Cronin has built are constructed from large polyoxometalates derived from a range of metal atoms, like tungsten. He gets them to assemble in bubbly spheres by mixing them in a specialized saline solution, and calls the resultant cell-like structures "inorganic chemical cells," or iCHELLs.
 
The metallic bubbles are certainly cell-like, but are they actually alive? Cronin has made a compelling case for the comparison by constructing the iCHELLS with a number of features that make them function much as real cells do. For instance, by modifying the outer oxide structure of the bubbles so that they are porous, he has essentially built iCHELLs with membranes capable of selectively allowing chemicals in and out according to size, much as what happens with the walls of real cells.
 
Cronin's team has also created bubbles inside of bubbles, which opens the door to the possibility of developing specialized "organelles." Even more compelling, some of the iCHELLs are being equipped with the ability to photosynthesize. The process is still rudimentary, but by linking some oxide molecules to light sensitive dyes, the team has constructed a membrane that splits water into hydrogen ions, electrons and oxygen when illuminated — which is how photosynthesis begins in real cells.
 
Of course, the most compelling lifelike quality of the iCHELLs so far is their ability to evolve. Although they aren't equipped with anything remotely resembling DNA, and therefore can't replicate themselves in the same way that real cells do, Cronin has nevertheless managed to create some polyoxometalates that can use each other as templates to self-replicate. Furthermore, he is currently embarked on a seven-month experiment to see if iCHELLs placed in different environments will evolve.
 
The early results have been encouraging. "I think we have just shown the first droplets that can evolve," Cronin hinted.
 
Though the idea of a strange new metal-based form of life rapidly evolving in a lab somewhere on Earth may sound ominous, the finding could forever change how life is defined. It also greatly improves the odds of life existing elsewhere in the universe, since life forms could potentially be built from any number of different elements.
 
The possibilities are exciting to imagine, even if Cronin's iCHELLs eventually fall short of full-blown living cells. His research may have already blown the door off previous paradigms about the conditions necessary for life to form.

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anonymous
anonomous Jan 05 2012 at 2:23 PM

if the cells are using each other as templates to self replicate then they can't evolve with out mutations or some kind of genetic variation to aid is the process of adaptation.

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anonymous
Anon Anthropologist Jan 14 2012 at 9:42 AM

If mistakes are made in the replication then there's the variation you're looking for. One doesn't need the gene for there to have variation. Variation can occur even in non gene types as long as it is possible for the self replicating unit to make imperfect replications.

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anonymous
Guest Jan 07 2012 at 5:47 PM

well at first life began with cell that self-replicated then they mutated(?) from asexual to sexual lifeforms. I assume the same can happen given enough time with these.

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anonymous
mark Jan 01 2012 at 5:24 PM

The first ancestor of Optimus Prime!

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anonymous
the dude Dec 30 2011 at 7:32 PM

terminator? t1000.

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anonymous
fenderflip Dec 29 2011 at 2:47 AM

And that became known as the day the machines were born.

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anonymous
Guest Jan 03 2012 at 3:07 AM

lmao . yess .

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anonymous
Enter your name Dec 28 2011 at 5:02 PM

absolutely fascinating!
although i wish it wasn't called iCHell (icy hell, or I see Hell) seems to be a bad move in the branding dept.

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anonymous
Enter your name Dec 28 2011 at 5:03 PM

absolutely fascinating!
although i wish it wasn't called iCHell (icy hell, or I see Hell) seems to be a bad move in the branding dept.

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anonymous
Guest Feb 02 2012 at 1:03 AM

Icy hell, as in something very unlikely ie. "When hell freezes over." Pretty clever actually.

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anonymous
Guest Dec 27 2011 at 11:37 PM

Rewriting the book of life... hardly... only merely studying it... No one even knows what life is... to its origin and purpose or meaning, or will...

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anonymous
auther 1 Dec 25 2011 at 8:13 AM

the only thing Ifind confusing about all your comments is
why the date is not wrtten day month year as in 25/12/11.
I find this very alien. Jonny english

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anonymous
Guest Dec 25 2011 at 3:31 PM

month/day/year is how its done in the US mate

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anonymous
Guest Jan 14 2012 at 1:22 PM

pfft ignorant American not everyone follows exactly what the us does.... dumbass

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anonymous
Guest Jan 22 2012 at 6:54 AM

Someone answered a question kindly and you called them a dumbass because they simply mentioned the U.S. (which was obviously 100% relevant)? Considering they used the word "mate", I doubt they're American, mate. Go get a grasp on civility or kill yourself. Either outcome is acceptable.

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anonymous
Guest Jan 14 2012 at 1:22 PM

pfft ignorant American not everyone follows exactly what the us does.... dumbass

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anonymous
ReturnStroke Dec 24 2011 at 12:01 AM

FUSHIGI!!!!!!!

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anonymous
divine love Dec 23 2011 at 8:37 PM

big difference between adapt and evolve, they are trying way to hard to prove other theories, big stretch, as usual.

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anonymous
Forrest Feb 02 2012 at 7:45 PM
Yes there is but from the tone of your post you do not seem to understand what that difference IS. Adaptation is a COROLLARY OF not a PRECURSOR TO evolution. Organisms accumulate information in their genetic code over time. This is a result of mutations caused by a number of factors. MOST are detrimental and cause disease or other malady which prevent the organism from successful reproduction. SOME provide characteristics that allow an organism to be statistically more successful in reproducing.
.... More
Over time those features will be dispersed into the population causing change. Evolution is a process of very large numbers of changes and very long periods of time in which those changes are refined by environmental factors.
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anonymous
Enter your name Dec 14 2011 at 9:49 PM

All i have to say is Transformers..

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anonymous
Enter your name Dec 14 2011 at 9:49 PM

There is a problem with this situation..life requires information..if information cannot be stored and recalled..life will not happen. Also...what sort of energy are these droplets using...they look like droplets of mercury to me...stinks of a hoax..where is the research evidence?

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anonymous
Guest Jan 07 2012 at 7:58 PM
You're thinking of information stored in a compact and codified form, like DNA or binary. But if these things reproduce by blueprinting each other, then they're essentially using their own bodies as the information. It's 1:1 mapping instead of transcription-translation as in our bodies. Think of it as a house or an apartment building: if you want to duplicate it, you don't necessarily need to upload digital files onto a hard drive in order to get the information you need. You could just as easily (
.... More
although less conveniently in this case) examine each brick one at a time and place a corresponding brick at another location a mile away. Eventually, you'd have an exact replica of the original without any intermittent documentation.
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anonymous
Guest Dec 19 2011 at 6:49 PM

The picture looks like mercury because it is mercury...the image title even says so. They don't have a photo of metal cells, apparently, so they used a generic one as fluff. I'm not saying you're wrong to be questioning this whole thing, just you should probably be aware that that photo isn't actually supposed to be the cells in question.

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anonymous
Red Dog Dec 14 2011 at 6:09 PM

Have we forgotten that non-carbon based life has already been proven to exist? Wasn't it confirmed last year that arsenic based bacteria was discovered in California?

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anonymous
Guest Dec 15 2011 at 3:15 AM
DNA and RNA have a backbone composed of 5-carbon sugars and phosphates (PO4) alternating with bases attached to the carbon rings. This organism was able to substitute the phosphate in its nucleic acids with an arsenic and 4 oxygens. Essentially, all of the processes of transcription, translation, and control of gene expression occur in the same way, however this extremophile is so extraordinary because nucleic acids are thought to be the very first organic molecules ever synthesized and they have
.... More
never been observed to have a different structure in any organism, be it bacteria or eukaryote. Carbon is still present in the structure of all the macromolecules in this organism including proteins and nucleic acids nucleic acids. The so-called organisms that are replicating seems fishy to me for this reason. There is no way of coding for, of synthesizing and sort of functional protein. Even if these scientists were able to create complexes that established chemiosmotic gradients and initiated the beginnings of photosynthesis, much like photosystem 1 and 2 in chloroplasts, they still were not able to synthesize ATP transcriptase, nor would they be able to create a system for the the cells to replicate their genome. To date, DNA is the only form of genetic coding known to work. I would be interested in seeing the methods of this experiment as well as citations and well analyzed results and data, instead of some article from an online publication. Perhaps you can't tell, but I am a skeptic.
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