Talk to people in their 40s, and they will likely remember kids who brought peanut butter sandwiches to school. Ask a parent today, and they’ll tell you that peanuts aren’t even allowed in the cafeteria.
Now, researchers at the Murdoch Childrens Research Institute in Australia report that they may have taken the first steps to finding a treatment for this common allergy.
In a clinical trial, 28 children with peanut allergies were given daily doses of the probiotic Lactobacillus rhamnosus in combination with peanut protein. The amount of probiotic stayed the same while the dose of peanut protein increased over time until the children were receiving two grams a day.
By the end of the trial, more than 80 percent of the children who received treatment (and not the placebo) were able to include peanuts in their diet.
"In the study the combined delivery of probiotic and oral immunotherapy was a safe and effective treatment for peanut allergy,” said lead researcher professor Mimi Tang of the findings. “However it is important to point out that this treatment must be only be given under close medical supervision as we are giving peanut[s] to children who are allergic to peanut[s], and children did have allergic reactions. Nevertheless, the likelihood of success was high — if nine children were given probiotic and peanut therapy, seven would benefit."
Tang added, "It appears that we have been able to modify the allergic response to peanut such that the immune system produces protective responses rather than a harmful response to the peanut protein."
Children were tested two to five weeks after stopping the treatment. The researchers behind the study believe that more tests need to be done to see if those same children maintain their peanut tolerance over time.
According to the Centers for Disease Control and Prevention (CDC), food allergies among children increased by 18 percent between 1997 and 2007, and food-related allergic reactions have become the most common cause of anaphylaxis in community health settings.
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