10. Great Slave Lake
Situated in Canada's Northwest Territories, Great Slave is the deepest lake in North America at a little more than 2,000 feet deep. It covers somewhere around 10,000 square miles, much of it frozen over for most of the year. The capital of the Northwest Territories, the town of Yellowknife (population: around 20,000), is on the lake's north shore.
Great Slave, named for the indigenous Slavey Indians of the area, is packed with trout and whitefish, but much of the area is filled with miners, digging first for gold and now for diamonds. Great Slave Lake is also a houseboat haven, and the setting for the Animal Planet survivalist series "Ice Lake Rebels."