Feeling a little forgetful lately? Maybe BPA is to blame.
A new study, published in the journal Synapse, found that mice exposed to low levels of bisphenol A (BPA) during early development had impaired memory and altered levels of anxiety later in life. The results support a growing body of research that suggests exposure to BPA early in life alters brain development and fetal development in infancy.
In the study, researchers compared untreated mice with mice fed one of two low doses of BPA — either 100 micrograms per kilogram per day or 500 ug/kg/day — from gestation through the puberty. These doses were chosen because they are well below the safe dose level of 50 milligrams/kilogram/day identified by the U.S. Environmental Protection Agency (EPA).
The researchers tested the rodents' levels of anxiety and ability to form memories. They also examined the how exposure altered neuron development and activity in specific areas of the brain.
The animals exposed to BPA were more anxious than their untreated peers when placed in situations such as an elevated platform or an unfamiliar environment. Both the low and the high doses of BPA resulted in decreased memory recall when the mice explored a Y-shaped maze. Both doses also changed regions of the brain that are important for controlling impulses and making memories.
This study offers just one more reason why BPA is one of the 12 products you should avoid ... and keep away from your kids.
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