A rare infection caused by a brain-eating amoeba has taken the life of a teenager in North Carolina this summer, CNN reports. The single-celled killer, known as Naegleria fowleri, is common in lakes and other freshwater sources, and thrives when temperatures are high and water levels are low.

N. fowleri enters through the nose and attacks the brain, usually killing its victim within two weeks, according to the Centers for Disease Control and Prevention. But while the amoeba is widespread, infections are rare because it's not a parasite and doesn't seek out human hosts. It only accidentally ends up in someone's nose, yet once it's there it may burrow into the skull in search of food. When it eats brain tissue, it causes "primary amoebic meningoencephalitis," which is almost always fatal.

About three people die annually from N. fowleri in the U.S. But the amoeba is more prevalent in warm, shallow waters — especially in the Southern U.S. — and "infections can increase during heat wave years," according to the CDC. According to the CDC, infections occur mainly in July, August and September.

People can't be infected with N. fowleri by swallowing contaminated water, the CDC explains; it's only dangerous when it enters via the nose, which offers easy access to the brain. Infections are most common in children and young adults — the median age of victims is 12 — possibly because they're more likely to dive, swim and play in water.

A look at amebic meningoencephalitis due to Naegleria fowleri. A look at amebic meningitis due to Naegleria fowleri. (Photo: CDC/ Dr. Govinda S. Visvesvara/Wikimedia Commons)

The source of infection is typically a lake, river or hot spring, and the teen who died this summer was believed to be riding in a raft when it overturned. A 2011 case in Louisiana was more unusual, though — the Associated Press reports a man was infected by tap water he squirted into his nose using a neti pot. Neti pots relieve allergies and sinus problems by washing out the nose and sinuses, but experts recommend disinfecting the water first by boiling or distilling it. Tests showed N. fowleri was living in the Louisiana man's household water pipes, but authorities concluded the contamination was isolated to his house, and found none of the amoebae in local water supplies.

The relative risk of an N. fowleri infection is still extremely low, the CDC points out. There were 37 cases documented from 2006 to 2015, for instance, while there were an average 3,536 drowning deaths annually in the U.S. from 2005 to 2014. Yet with such high stakes involved, it's worth being aware of the threat and how to avoid it. Below is a list of symptoms, infection sources and safety tips from the CDC:


Initial symptoms (starting one to seven days after infection) include: headache, fever, nausea, vomiting and stiff neck. Later symptoms include: confusion, lack of attention, loss of balance, seizures and hallucinations. After the start of symptoms, the disease progresses rapidly and usually causes death within one to 12 days.

Infection sources

N. fowleri is not found in the ocean or other saltwater, but it may inhabit the following:

  • Bodies of warm freshwater, such as lakes and rivers
  • Geothermal water, such as hot springs
  • Warm-water discharge from industrial plants
  • Geothermal drinking-water sources
  • Swimming pools that are poorly maintained and/or minimally chlorinated
  • Water heaters with temperatures less than 116º F
  • Soil
Safety tips

As the CDC warns, "The only certain way to prevent a Naegleria fowleri infection is to refrain from water-related activities in or with warm, untreated or poorly treated water." But since a low risk "will always exist with recreational use of warm freshwater," the agency also offers a few tips for minimizing your odds of infection:

  • Avoid water-related activities in warm freshwater during periods of high water temperature and low water levels.
  • Hold the nose shut or use nose clips when taking part in water-related activities in bodies of warm freshwater.
  • Avoid digging in, or stirring up, the sediment while taking part in water-related activities in shallow, warm freshwater areas.

This story was originally published in August 2011 and has been updated with new information.

Russell McLendon ( @russmclendon ) writes about humans and other wildlife.

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