In honor of World Malaria Day, celebrities supporting the organization Malaria No More have joined together to create a PSA urging people to help eradicate the mosquito-borne infectious disease.

Each year, more than 225 million cases of malaria are reported, resulting in close to 1 million deaths. Most of the dead are children in sub-Saharan Africa who lack access to sufficient protection and treatment. Malaria No More raises funds to provide equipment and people at the source. 

Two weeks ago, the organization held a live comedy fundraiser called "Hollywood Bites Back" featuring celebrities like Sarah Silverman, Conan O’Brien, Elizabeth Banks and B.J. Novak from "The Office." A stunning $750,000 was generously given during the event. 

Many of those names appear in this new PSA, as well as a David Spade and Ed Helms. Check it out below — and please consider visiting the Malaria No More website to make a donation and help end this disease.  

Michael d'Estries ( @michaeldestries ) covers science, technology, art, and the beautiful, unusual corners of our incredible world.