In honor of World Malaria Day, celebrities supporting the organization Malaria No More have joined together to create a PSA urging people to help eradicate the mosquito-borne infectious disease.

Each year, more than 225 million cases of malaria are reported, resulting in close to 1 million deaths. Most of the dead are children in sub-Saharan Africa who lack access to sufficient protection and treatment. Malaria No More raises funds to provide equipment and people at the source. 

Two weeks ago, the organization held a live comedy fundraiser called "Hollywood Bites Back" featuring celebrities like Sarah Silverman, Conan O’Brien, Elizabeth Banks and B.J. Novak from "The Office." A stunning $750,000 was generously given during the event. 

Many of those names appear in this new PSA, as well as a David Spade and Ed Helms. Check it out below — and please consider visiting the Malaria No More website to make a donation and help end this disease.  

Michael d'Estries ( @michaeldestries ) covers science, technology, art, and the beautiful, unusual corners of our incredible world.

Celebs speak out on World Malaria Day
Conan O'Brien, Sarah Silverman and many other stars come together to say let's make malaria no more this World Malaria Day.